Towards standardized reporting in studies of encapsulating peritoneal sclerosis.

نویسندگان

  • Mark Lambie
  • Niko Braun
  • Simon J Davies
چکیده

Encapsulating peritoneal sclerosis (EPS), a serious but uncommon complication of peritoneal dialysis (PD), initially well described in the Japanese patient population (1–3), is now widely recognized. Because of the severe morbidity and mortality attached, EPS has the potential to negatively affect perceptions of the value of PD as a long-term therapy and so affect the take-on rate and increase early transfer to HD. It is now well established that EPS is strongly associated with duration of PD therapy (4,5), with ultrafiltration failure associated with membrane fibrosis (6,7), and also, paradoxically, with stopping PD. Nevertheless, significant deficits in the understanding of EPS remain. That lack of understanding is implicit in nonspecific diagnostic criteria and an uncertain association with peritonitis, issues that arise in a study by Wong et al. (8) in this issue of Peritoneal Dialysis International.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Successful treatment of encapsulating peritoneal sclerosis with immunosuppressive therapy.

Encapsulating peritoneal sclerosis is a rare, but potentially lethal, complication of peritoneal dialysis. Treatment of patients with encapsulating peritoneal sclerosis is controversial. Conservative treatment carries a poor outcome, and immunosuppressive drugs are now used frequently. Most commonly, these immunosuppressive regimens include steroids with or without azathioprine or cyclosporine....

متن کامل

Encapsulating peritoneal sclerosis--a complication of peritoneal dialysis.

Encapsulating peritoneal sclerosis (EPS) is a rare complication of peritoneal dialysis. It often presents with non-specific symptoms, leading to a delay in diagnosis and a poor prognosis. Here we report a case of EPS in a patient treated with peritoneal dialysis and discuss the risk factors, diagnostic challenges and treatment options available.

متن کامل

Encapsulating peritoneal sclerosis--a clinician's approach to diagnosis and medical treatment.

Encapsulating peritoneal sclerosis (EPS) is recognized as a serious complication of continuous peritoneal dialysis. A preliminary diagnosis of EPSis usually based on clinical signs and symptoms, which commonly include abdominal pain, nausea, vomiting, anorexia, abdominal fullness, an abdominal mass, bowel obstruction, and radiologic findings, including abdominal roentgenogram, contrast studies,...

متن کامل

Histological Criteria for Encapsulating Peritoneal Sclerosis – A Standardized Approach

BACKGROUND The two most relevant pathologies of long-term peritoneal dialysis (PD) are simple sclerosis and encapsulating peritoneal sclerosis (EPS). The histological differentiation of those two entities is difficult. The Aim of the study was to establish a method to standardize and facilitate the differentiation between simple sclerosis and EPS METHODS: We investigated 58 peritoneal biopsies...

متن کامل

Prospective multicenter observational study of encapsulating peritoneal sclerosis with neutral dialysis solution--the NEXT-PD study.

Many observational studies have been conducted on the occurrence of encapsulating peritoneal sclerosis (EPS). However, poorly biocompatible acidic glucose-based dialysis solutions were used in all previous studies. Today, dialysis solutions that are more biocompatible have become widely available. We therefore initiated a new prospective observational study on the occurrence of EPS. The study d...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

دوره 33 5  شماره 

صفحات  -

تاریخ انتشار 2013